125995-03-1, Atorvastatin lactone is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Compound 42 (100 mg, 185 muiotaetaomicron) was dissolved (0514) in ammonia (7Nin MeOH, 1.32 mL, 6.18 mmol) and the (0515) solution was stirred at rt for 24 h. The mixture was (0516) concentrated under reduced pressure. Purification by (0517) flash chromatography (CH2Cl2:MeOH = 95:5? 90: 10) (0518) afforded 43 as a white foam (73 mg, 71%). NMR (0519) (400 MHz, CDCls) delta 7.24-6.95 (m, 14H), 6.88 (br s, 1H), 5.73 (br s, 1H), 5.44 (br s, 1H), 4.42 (br s, 1H), 4.20-4.05 (m, 2H), 4.01-3.90 (m, 1H), 3.79-3.71 (m, 1H), 3.63-3.48 (m, 2H), 2.34-2.23 (m, 2H), 1.74-1.41 (m, 9H), 1.28-1.14 (m, 1H).
125995-03-1 Atorvastatin lactone 6483036, aTetrahydropyrans compound, is more and more widely used in various.
Reference£º
Patent; STICHTING KATHOLIEKE UNIVERSITEIT; SCHIRRIS, Tom Johan Joseph; RITSCHEL, Tina; RUTJES, Floris Petrus Johannes Theodorus; SMEITINK, Johannes Albertus Maria; RUSSEL, Francois Gerard Marie; (92 pag.)WO2017/137469; (2017); A1;,
Tetrahydropyran – Wikipedia
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