36838-71-8, 4-Methylenetetrahydro-2H-pyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Intermediate HKi): 1 ,6-dioxaspiro[2.5]octaneA solution of 4-methylenetetrahydro-2H-pyran (1.00 g, 10.2 mmol) in CH2CI2 (30 ml.) was placed in an ice bath then mef¡ã-chloroperoxybenzoic acid (2.46 g, 14.3 mmol) was added in three portions. The reaction was slowly warmed to RT and stirred for 3h then quenched with 10% NaOH(aq) (10 mL) and extracted with CH2CI2 (2 x 15 ml_). The combined extracts were dried (MgSO4), filtered and concentrated to provide intermediate HlXi) as a clear oil (607 mg, 52%). 1H NMR (300 MHz, CHLOROFORM-d) delta ppm 1.45 – 1.63 (m, 2 H), 1.76 – 1.99 (m, 2 H), 2.69 (s, 2 H), 3.71 – 3.95 (m, 4 H).
As the paragraph descriping shows that 36838-71-8 is playing an increasingly important role.
Reference£º
Patent; PFIZER INC.; WO2008/125945; (2008); A2;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics