33024-60-1, Tetrahydro-2H-pyran-4-amine hydrochloride is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step D; To a mixture of the compound described in Step C, Example 2 (240 mg, 0.455 mmol), 4- amino tetrahydrofuran HC1 salt (63 mg, 0.455 mmol), molecular sieve (9i, 200 mg), DIEA (7011L, 0.455 mmol) in DCM (15 mL), was added sodium triacetoxyborohydride (482 mg, 2.275 mmol) and the resulting mixture was stirred overnight at room temperature. The reaction was diluted with DCM, filtered through celite, and evaporated i7l vacuo. The residue was purified by preparative TLC (1000 micron, eluant: 6percent MeOH : 94percent DCM) to afford two separate single isomers (isomer 1, less polar, 75 mg, 28percent ; isomer 2, more polar, 58 mg, 22percent).
As the paragraph descriping shows that 33024-60-1 is playing an increasingly important role.
Reference£º
Patent; MERCK & CO., INC.; WO2005/80371; (2005); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics