5631-96-9, 2-(2-Chloroethoxy)tetrahydro-2H-pyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To the compound 3 (39.12 g, 0.24 mol) was added diethanolamine (25.23 g 0.24 mol), Na2CO3 (31.80 g, 0.30 mol), NaI (2g, 13.34mmol), TBAB (0.3 g) and DMF (60 mL), and then stirred at 140 C for 5 hours. The solvent DMF was evaporated in vacuo. Then ethyl acetate (100 mL) and 10% NaCl solution (100 mL) were added in sequence, and stirred for 5 minutes. The aqueous phase was separated and the organic phase was washed with 100 mL of 10% aqueous NaCI, dried over anhydrous Na2SO4, and evaporated in vacuo to give 2,2′-((2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)amino)bis(ethane-1-ol) (Compound 4), pale yellow oil, 50.39 g, yield 90%. It was used directly in the next synthesis without further purification.
The synthetic route of 5631-96-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Zhai Xuexu; (9 pag.)CN108774215; (2018); A;,
Tetrahydropyran – Wikipedia
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