Brief introduction of 3301-94-8

3301-94-8, The synthetic route of 3301-94-8 has been constantly updated, and we look forward to future research findings.

3301-94-8, 6-Butyltetrahydro-2H-pyran-2-one is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Delta-nonalactone (manufactured by Sigma-Aldrich, 15.6 g, 0.10 mol) and 99% ethanol (270.0 g) were charged in a 500 mL four-necked flask and stirred at 25 C. to 30 C./30 Sodium ethoxide (manufactured by Sigma-Aldrich, 21% ethanol solution, 5.5 g, 0.017 mol) is added dropwise under the conditions of 100 ml / min. After stirring overnight at room temperature, glacial acetic acid (1.0 g, 0.017 mol) was added for neutralization and concentration under reduced pressure. 15% saline (100 g) was added to the obtained residue, and the mixture was extracted with ether (100 g). The obtained organic layer was washed with 5% aqueous sodium hydrogencarbonate solution (100 g) and 15% saline (100 g) . The extract was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give ethyl 5-hydroxynonanoate (19.8 g) as a colorless oily crude product. Crude yield 98%

3301-94-8, The synthetic route of 3301-94-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; T. Hasegawa Co., Ltd.; Kawabata, Kazuya; Kazuya, Daichi; Haraguchi, Kenji; Takaku, Hiroyasu; (16 pag.)JP2015/131773; (2015); A;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics