1194-16-7, 2,2-Dimethyltetrahydropyran-4-one is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of 2,2-dimethyltetrahydropyran-4-one 1 (1.3 g, 0.01 mol)[8], furfural (1.0 g, 0.01 mol), ethyl cyanoacetic acid (1.1 g,0.01 mol), and ammonium acetate (6.2 g, 0.08 mol) in 30 mL of absolute ethanol was boiled with stirring for 6 h. After cooling, the crystals were filtered off, washed with water, diethyl ether, dried and recrystallized from ethanol. Yield 1.3 g (49 %), mp 289-290 C. IR spectrum, nu, cm-1: 3300, 3150, 3050 (N-H, C-H), 2240 (C?N), 1650 (C=O). 1H NMR spectrum, delta, ppm: 1.29 s (6H, 2CH3), 2.54 br. s(2H, CH2), 4.55 br. s (2H, OCH2), 6.68 d. d (1H, H4furan,J = 3.6, 1.7 Hz), 7.24 br. d (1H, H3furan, J= 3.6 Hz), 7.80 d.d (1H, H5furan, J = 1.7, 0.6 Hz), 12.46 br. s (1H, NH). 13C NMR spectrum, delta, ppm: 25.8, 37.3, 59.5, 68.8, 103.6, 108.0, 111.8, 115.6, 115.8, 143.7, 144.8, 146.1, 146.4, 159.9. Found, % C 66.59; H 5.31; N 10.32. C15H14N2O3. Calculated, %: C 66.66; H 5.22; N 10.36., 1194-16-7
As the paragraph descriping shows that 1194-16-7 is playing an increasingly important role.
Reference£º
Article; Dabaeva; Baghdasaryan; Paronikyan; Tamazyan; Ayvazyan; Dashyan, Sh. Sh.; Russian Journal of General Chemistry; vol. 89; 12; (2019); p. 2364 – 2368; Zh. Obshch. Khim.; vol. 89; 12; (2019); p. 1842 – 1847,6;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics