4295-99-2,4295-99-2, 4-Cyanotetrahydro-4H-pyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Lithium bis(trimethylsilyl)amide (1M in THF, 27 mL, 27 mmol) was added dropwise to a solution ofoxane-4-carbonitrile (2.0 g, 18 mmol) in THF (10 mL) at 0 C. The reaction mixture was warmed to rt,stirred for 10 min and cooled back to 0 C. Allyl bromide (3.30 g, 27 mmol) was added dropwise, thesolution warmed to room temperature and stirred overnight. The reaction mixture wasconcentrated in vacuo and saturated aqueous NH4Cl (20 mL) was added. The phases were separatedand the aqueous phase was extracted with EtOAc (3 ¡Á 50 mL). The combined organic extracts weredried and concentrated in vacuo to give the amine (2.37 g, [87%]) as a colourless oil that was usedstraight in the next step.
As the paragraph descriping shows that 4295-99-2 is playing an increasingly important role.
Reference£º
Article; Craven, Philip; Aimon, Anthony; Dow, Mark; Fleury-Bregeot, Nicolas; Guilleux, Rachel; Morgentin, Remy; Roche, Didier; Kalliokoski, Tuomo; Foster, Richard; Marsden, Stephen P.; Nelson, Adam; Bioorganic and Medicinal Chemistry; vol. 23; 11; (2015); p. 2629 – 2635;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics