951127-25-6, tert-Butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
At room temperature, A solution of 1a (0.215 g, 0.62 mmol) was dissolved N,N-dimethylacetamide (4 mL) was added intermediate 1 (0.225 g, 0.69 mmol), and the mixture was stirred at room temperature for 1 hour. Cooling to 0C ,Sodium tris(acetoxy)borohydride (0.171 g, 0.806 mmol) was added to the reaction solution, Add natural to room temperature reaction for 16 hours.The reaction solution was cooled to 0 C, water (20 mL) was added in that order, and the pH was adjusted to 8 with aqueous ammonia (2 mL). The organic phase was extracted with dichloromethane (50 mL x 3), washed with saturated brine solution (50 mL x 1) Dried over anhydrous magnesium sulfate, filtered, and the filtrate was concentrated and purified by column chromatography (dichloromethane / methanol (v / v) = 30: 1) to give yellow solid 1b (0.179 g, 56.1% yield)., 951127-25-6
As the paragraph descriping shows that 951127-25-6 is playing an increasingly important role.
Reference£º
Patent; Sichuan Haisco Pharmaceutical Co.,Ltd.; FAN, JIANG; ZHANG, CHEN; PENG, FEI; WU, YE; FENG, JIANCHUAN; WANG, JIANMIN; ZHENG, SUXIN; WEI, YONGGANG; YE, FEI; (350 pag.)TW2017/8220; (2017); A;,
Tetrahydropyran – Wikipedia
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