Downstream synthetic route of 125552-89-8

125552-89-8 4-(Bromomethyl)tetrahydropyran 2773286, aTetrahydropyrans compound, is more and more widely used in various fields.

125552-89-8, 4-(Bromomethyl)tetrahydropyran is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Intermediate A1 Kv): (2S,5R)-1-benzyl-2,5-dimethyl-4-(tetrahydro-2/-/-pyran-4- ylmethyl)piperazine.; To a microwave vial was added A11(iv) (7.5Og, 36.7 mmol),(bromomethyl)tetrahydropyran (6.57g, 36.7 mmol), triethylamine (12.8 ml_, 91.8 mmol), and MeOH (9 mL). The reaction mixture was heated to 150 0C for 2 hours in the microwave, at which time the resulting solid was triturated withMeOH, filtered, and dried to give the desired product as a white solid A11 (v) (6.1 g, 55%). Mass Spectrum: Calcd for Ci9H31N2O (M+H): 303. Found: 303., 125552-89-8

125552-89-8 4-(Bromomethyl)tetrahydropyran 2773286, aTetrahydropyrans compound, is more and more widely used in various fields.

Reference£º
Patent; PFIZER INC.; WO2008/96260; (2008); A1;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics