1197-66-6, 2,2,6,6-Tetramethyl-2H-3,5,6-trihydropyran-4-one is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a 10 mL round bottom flask was added ketone compound A (700 mg, 4.48 mmol), acetic acid (26.0 muL, 0.452 mmol), ethyl cyanoacetate (477 muL, 4.48 mmol) and piperidine (45.0 muL, 0.452 mmol) Was added at 0C. After the temperature was changed to room temperature, acetic acid (26.0 L, 0.452 mmol) and piperidine (45.0 L, 0.452 mmol) were added one more time. After stirring at room temperature for 1.5 hours, sodium bicarbonate aqueous solution (3 mL) was added to the resulting suspension, which was extracted three times with ethyl acetate (3 mL). The organic layer was collected, water was removed with anhydrous sodium sulfate, filtered and concentrated. The resulting solution was separated by silica gel column chromatography (hexanes / EtOAc, 5: 1) to obtain ethyl 2-cyano-2-(2,2,6,6-tetramethyldihydro-2H-pyran-4(3H)-ylidene)acetate, compound B) (586 mg, 2.33 mmol, 52%).
1197-66-6, As the paragraph descriping shows that 1197-66-6 is playing an increasingly important role.
Reference£º
Patent; Research Business Foundation SUNGKYUNKWAN UNIVERSITY; Jae, Youl Cho; Yang, Woo Seok; Baek, Kwang Soo; Sung, Nak Yoon; Lee, Yun Mi; Mun, Bo Hyun; (34 pag.)KR2017/88140; (2017); A;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics