389621-77-6, 2-(Tetrahydro-2H-pyran-4-yl)ethanamine hydrochloride is a Tetrahydropyrans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
2-Bromo-N-(3,5-dibromopyrazin-2-yl)acetamide (3.30 g, 8.83 mmol) and 2-(tetrahydro-2H-pyran-4-yl)ethanamine hydrochloride (1.46, 8.83 mmol) and diisopropyl ethylamine (6.67 mL, 35.3 mmol) were combined and heated at 85 C. Upon complete consumption of starting material (by TLC), the reaction solution was condensed and purified using silica gel column chromatography (0-100% ethyl acetate in hexanes) to afford the title compound (1.53 g, 4.48 mmol, 50% yield).
389621-77-6, The synthetic route of 389621-77-6 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Mortensen, Deborah S.; Sapienza, John; Lee, Branden G.S.; Perrin-Ninkovic, Sophie M.; Harris, Roy; Shevlin, Graziella; Parnes, Jason S.; Whitefield, Brandon; Hickman, Matt; Khambatta, Gody; Bisonette, Rene R.; Peng, Sophie; Gamez, Jim C.; Leisten, Jim; Narla, Rama Krishna; Fultz, Kimberly E.; Sankar, Sabita; Bioorganic and Medicinal Chemistry Letters; vol. 23; 6; (2013); p. 1588 – 1591;,
Tetrahydropyran – Wikipedia
Tetrahydropyran – an overview | ScienceDirect Topics