Archives for Chemistry Experiments of 40191-32-0

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 40191-32-0, help many people in the next few years., Electric Literature of 40191-32-0

Electric Literature of 40191-32-0, An article , which mentions 40191-32-0, molecular formula is C6H9ClO2. The compound – Tetrahydro-2H-pyran-4-carbonyl chloride played an important role in people’s production and life.

Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors

Herein we report the successful incorporation of a lactam as an amide replacement in the design of hepatitis C virus NS5B Site II thiophene carboxylic acid inhibitors. Optimizing potency in a replicon assay and minimizing potential risk for CYP3A4 induction led to the discovery of inhibitor 22a. This lead compound has a favorable pharmacokinetic profile in rats and dogs.

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Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics