The Absolute Best Science Experiment for Tetrahydro-2H-pyran-3-ol

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Hydroboration of Prochiral Olefins with Chiral Lewis Base-Borane Complexes: Relationship to the Mechanism of Hydroboration

Alcohols with up to 19percent enantiomeric excess were obtained on hydroboration/oxidation of representative prochiral olefins using N-isobornyl-N-methylaniline-borane or N-benzyl-N-isopropyl-alpha-methylbenzylamine-borane indicating that the Lewis base is present in the hydroboration transition state.

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Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics