Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 499-40-1, Name is (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal, Quality Control of: (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal.
DNA binding, cytotoxicity and DNA cleavage promoted by gold(III) complexes
Square planar Au(III) complexes of 2,2?-dipyridylamine (A 1), di(2-pyridyl)ketone (A2), 2-(4-chlorophenyl)-1H- imidazo[4,5-f] [1,10] phenanthroline (A3) and 2-(4-bromophenyl)-1H- imidazo[4,5-f][1,10] phenanthroline (A4) of type [Au(A n)Cl2].Cl were synthesized and characterized using conductivity measurement, C,H,N elemental analysis, FT-IR, LC-MS, 1H and 13C NMR spectroscopy. The compounds manifested significant cytotoxic properties in vitro for brine shrimp lethality bioassay. The metal complexes were screened for series of DNA binding activity using UV-vis. absorption titration, hydrodynamic measurement and thermal DNA denaturation study. The nucleolytic activity was performed on plasmid pUC19 DNA. The Michaelis-Menten kinetic studies were performed to evaluate rate of enhancement in metal complexes mediated DNA cleavage over the noncatalyzed DNA cleavage.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Quality Control of: (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal. In my other articles, you can also check out more blogs about 499-40-1
Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics