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In an article, published in an article, once mentioned the application of 499-40-1, Name is (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal,molecular formula is C12H22O11, is a conventional compound. this article was the specific content is as follows.SDS of cas: 499-40-1
Manganese(ii) complexes with the non-steroidal anti-inflammatory drugs naproxen and mefenamic acid: Synthesis, structure, antioxidant capacity, and interaction with albumins and DNA
The interaction of the non-steroidal anti-inflammatory drugs naproxen or mefenamic acid with MnCl2 in the presence of the nitrogen-donor ligands 2,2?-bipyridine, 1,10-phenanthroline, 2,2?-bipyridylamine or pyridine resulted in the formation of one dinuclear and four mononuclear Mn(ii) complexes. The complexes were characterized by diverse physicochemical and spectroscopic techniques and single-crystal X-ray crystallography. The biological activity of the complexes was evaluated in regard to their ability to scavenge the free radicals of 1,1-diphenyl-2-picrylhydrazyl, 2,2?-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and hydroxyl and their binding affinity towards calf-thymus (CT) DNA and serum albumins. The complexes exhibit noteworthy scavenging activity towards ABTS and hydroxyl radicals; they can bind tightly to CT DNA via intercalation and can bind to bovine or human serum albumins tightly and reversibly.
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Reference£º
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics