Electric Literature of 2081-44-9, An article , which mentions 2081-44-9, molecular formula is C5H10O2. The compound – Tetrahydro-2H-pyran-4-ol played an important role in people’s production and life.
We have previously reported the syntheses of a series of 3,6-disubstituted quinolines as modulators of the retinoic acid receptor-related orphan receptor gamma t (RORgammat). These molecules are potent binders but are high molecular weight and they exhibited poor solubility at pH 2 and pH 7. This manuscript details our efforts at improving physical chemical properties for this series of compounds by increasing the diversity at the 3-position (i.e. introducing heteroatoms and lowering the molecular weight). These efforts have led to molecules which are potent binders with improved solubility.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 2081-44-9, help many people in the next few years., Electric Literature of 2081-44-9
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Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics