Application of 14215-68-0. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 14215-68-0, Name is N-((2S,3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide. In a document type is Article, introducing its new discovery.
Partial Purification and Characterization of Rat Mammary Gland Lectin
A carbohydrate binding protein was found in mid-lactating rat mammary gland.This rat mammary gland lectin agglutinated trypsinized rabbit erythrocytes and the heagglutination was inhibited by the addition of beta-D-galactosides such as lactose, melibiose, UDP-galactose and thio-D-galactoside.The lectin was partially purified by affinity chromatography on a column of Sepharose 4B to which asialo-fetuin had been covalently linked.Rat mammary gland lectin is a glycoprotein with a molecular weght of 14,800 estimated from SDS-PAGE, or 16,800 from gel-filtration.The occurence of two glycoproteins, C4-casein and alpha-lactalbumin, is known in rat milk.Bovine kappa-casein is well-characterized glycoprotein.These glycoproteins were found to be bound by the rat mammary gland lectin, when they were desialylated by the action of neuraminidase.Neuraminidase-untreated alpha-lactalbumin also bound to the lectin but to a lesser extent.The level of the lectin in rat mammary gland was greatly reduced during regression of the gland after weaning.
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Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics