Electric Literature of 65412-03-5. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 65412-03-5, Name is 4-(2-Aminoethyl)tetrahydro-2H-pyran. In a document type is Article, introducing its new discovery.
We have identified tryptophan-based selective nanomolar butyrylcholinesterase (BChE) inhibitors. They are defined according to their chemical modularity, novel binding mode revealed by five solved crystal structures with human BChE, low cytotoxicity, and predicted permeability of the blood-brain barrier. Altogether, these factors indicate their potential as unique lead compounds for symptomatic therapy against Alzheimer’s disease.
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Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics