A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 14215-68-0, Name is N-((2S,3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide, molecular formula is C8H15NO6. In a Patent，once mentioned of 14215-68-0, Application In Synthesis of N-((2S,3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide
A new class of molecules, C1-OH tributanoylated hexosamines, including, for example, Ga1NAc, G1cNAc and ManNAc, are demonstrated to increase cartilage-like tissue accumulation by IL- 1beta-stimulated chondrocytes. Furthermore, all three molecules reduced NFKB1 and IotakappaBetaalpha driven gene expression, consistent with NFkappaB inhibitory properties of these analogs. Ga1NAc-a exposure produced the greatest ECM accumulation by IL-Iotabeta- stimulated chondrocytes. However, Ga1NAc-a exposure produced an opposite effect on MSC exposure, where a decrease in ECM accumulation was observed. These findings are in support of the function of NFkappaB signaling during limb development and growth plate chondrogenesis. The present invention shows the capability of this new class of hexosamine analogs as disease-modifying agents for treating cartilage damage.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data.Application In Synthesis of N-((2S,3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 14215-68-0, in my other articles.
Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics