Extracurricular laboratory:new discovery of Tetrahydropyran-4-carbaldehyde

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In an article, published in an article, once mentioned the application of 50675-18-8, Name is Tetrahydropyran-4-carbaldehyde,molecular formula is C6H10O2, is a conventional compound. this article was the specific content is as follows.COA of Formula: C6H10O2

A new and concise protocol for selective reduction of N,N-dimethylamides into aldehydes was established using sodium hydride (NaH) in the presence of sodium iodide (NaI) under mild reaction conditions. The present protocol with the NaH-NaI composite allows for reduction of not only aromatic and heteroaromatic but also aliphatic N,N-dimethylamides with wide substituent compatibility. Retention of alpha-chirality in the reduction of alpha-enantioriched amides was accomplished. Use of sodium deuteride (NaD) offers a new step-economical alternative to prepare deuterated aldehydes with high deuterium incorporation rate. The NaH-NaI composite exhibits unique chemoselectivity for reduction of N,N-dimethylamides over ketones.

Do you like my blog? If you like, you can also browse other articles about this kind. COA of Formula: C6H10O2. Thanks for taking the time to read the blog about 50675-18-8

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics