Synthetic Route of 50675-18-8. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Like 50675-18-8, Name is Tetrahydropyran-4-carbaldehyde. In a document type is Article, introducing its new discovery.
The intramolecular carbocyclization of difluorinated enol acetals has been achieved for the first time using gold(I) catalysis. Difluorinated enol acetals bearing a pendant alkene group can be cyclized and reduced in one pot to form fluorinated diol motifs. Alternatively, the cyclization of terminal alkynes allows for the synthesis of fluorinated pyran scaffolds. Both cyclization processes can be performed under mild conditions allowing access to complex products rich in functionality. The cyclic systems are synthesized concisely (maximum four steps) from trifluoroethanol, an inexpensive fluorinated feedstock.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 50675-18-8, help many people in the next few years., Synthetic Route of 50675-18-8
Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics