Electric Literature of 51673-83-7. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Like 51673-83-7, Name is Tetrahydro-2H-pyran-2-carboxylic acid. In a document type is Article, introducing its new discovery.
Treatment of trans-epoxides 3 with Co2(CO)8 gave the corresponding cobalt complexes, which were subsequently exposed to a catalytic amount of BF3·OEt2 at -78C to provide exclusively cis-2-ethynyl-3- hydroxytetrahydropyran derivatives via endo mode cyclization pathway. cis- Congeners, cis-3 afforded the corresponding trans tetrahydropyran derivatives exclusively. This novel cyclization has been found to proceed with retention of configuration at the propynyl stereogenic center. Requirement for stereoselectivity in cyclization was discussed.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 51673-83-7. You can get involved in discussing the latest developments in this exciting area about 51673-83-7
Reference：
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics