1-Sep-2021 News The Best Chemistry compound: 3-Methoxydihydro-2H-pyran-4(3H)-one

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Chemistry, like all the natural sciences, begins with the direct observation of nature— in this case, of matter. 624734-17-4, Name is 3-Methoxydihydro-2H-pyran-4(3H)-one, molecular formula is C6H10O3. In a Article,once mentioned of 624734-17-4, 624734-17-4

We report the discovery of a potent, selective, and orally bioavailable dual CCR2 and CCR5 antagonist (3S,4S)-N-[(1R,3S)-3-isopropyl-3-({4-[4- (trifluoromethyl)pyridin-2-yl]piperazin-1-yl}carbonyl)cyclopentyl] -3-methoxytetrahydro-2H-pyran-4-amine (19). After evaluation in 28-day toxicology studies, compound 19 (INCB10820/PF-4178903) was selected as a clinical candidate.

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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics