The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane( cas:97739-46-3 ) is researched.Application of 97739-46-3.Ohnmacht, Stephan A.; Brenstrum, Tim; Bleicher, Konrad H.; McNulty, James; Capretta, Alfredo published the article 《Solid-phase Suzuki cross-coupling reactions using a phosphine ligand based on a phospha-adamantane framework》 about this compound( cas:97739-46-3 ) in Tetrahedron Letters. Keywords: polymer supported haloarene arylboronic acid coupling palladium phospha adamantane; biaryl preparation; palladium phospha adamantane Suzuki coupling catalyst. Let’s learn more about this compound (cas:97739-46-3).
The use of a catalyst system based on Pd2dba3·CHCl3 and 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phospha-adamantane allowed for Suzuki coupling aryl halides with an array of boronic acids on a solid-phase platform. The reactions can be carried out at room temperature with low palladium loadings in high yields.
If you want to learn more about this compound(1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane)Application of 97739-46-3, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(97739-46-3).
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics