Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 16400-32-1, is researched, Molecular C5H7Br, about Synthesis of 1,2-fused tricyclic indoles via Cu-/base-mediated hydroamination of alkynes, the main research direction is fused tricyclic indole preparation; alkynylthioindole hydroamination copper catalyst.Application In Synthesis of 1-Bromo-2-pentyne.
Synthesis of a variety of 1,2-fused tricyclic S-containing indoles is reported starting from indole sulfides tethered with terminal and internal alkynes via a key hydroamination step. Cu-catalyzed hydroamination reactions resulted in the exclusive formation of tricycles possessing an exocyclic methylene moiety, whereas base-mediated conditions led to thiazolo[3,2-a]indoles. Indole sulfides with internal alkyne functionality produced 2H-[1,3]thiazino[3,2-a]indoles under Cu-catalysis.
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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics