Cabrera-Lobera, Natalia; Quiros, M. Teresa; Bunuel, Elena; Cardenas, Diego J. published the article 《Atom-economical regioselective Ni-catalyzed hydroborylative cyclization of enynes: development and mechanism》. Keywords: borylative cyclization enyne ether amine preparation alkylidenecycloalkane boronate; alkylidene cyclopentane pyrrolidine piperidine boronate preparation borylative cyclization enyne.They researched the compound: 1-Bromo-2-pentyne( cas:16400-32-1 ).COA of Formula: C5H7Br. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:16400-32-1) here.
We report a full study on the novel regioselective Ni-catalyzed hydroborylative cyclization of enynes using HBpin as the borylation agent. Alkyl and alkenyl boronates can be obtained depending on the substituent on the alkyne. The reaction takes place under smooth conditions with an inexpensive catalytic Ni-based system, constituting a fully atom-economic eco-friendly method. This process shows a broad scope, allowing the formation of carbo- and heterocycles in moderate to good yields. The utility of the resulting boronates is also illustrated. We have studied the reaction mechanism both exptl. and computationally. The process involves initial oxidative cyclometalation to Ni(0)(xantphos) species followed by the key C-B bond formation through σ-bond metathesis and reductive elimination.
Here is a brief introduction to this compound(16400-32-1)COA of Formula: C5H7Br, if you want to know about other compounds related to this compound(16400-32-1), you can read my other articles.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics