The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Convenient synthesis of dioxopiperazines via aminolysis of α-(pyruvylamino) esters》. Authors are Marshall, J. A.; Schlaf, T. F.; Csernansky, J. G..The article about the compound:Ethyl indoline-2-carboxylatecas:50501-07-0,SMILESS:O=C(C1NC2=C(C=CC=C2)C1)OCC).SDS of cas: 50501-07-0. Through the article, more information about this compound (cas:50501-07-0) is conveyed.
Dioxopiperazines I and II were prepared from indoline III by cyclizing with MeNH2 to give dioxopiperazine IV, which was dehydrated to methylene compound V. V added AcSH to give I and II. Analogous reactions starting with pyrrole VI gave dioxopiperazine VII.
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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics