The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-Bromo-2-pentyne(SMILESS: CCC#CCBr,cas:16400-32-1) is researched.Application In Synthesis of 4-Aminopyrimidine. The article 《Palladium-Catalyzed Carbo-Oxygenation of Propargylic Amines using in Situ Tether Formation》 in relation to this compound, is published in Chemistry – A European Journal. Let’s take a look at the latest research on this compound (cas:16400-32-1).
This work reported a new method for the palladium-catalyzed oxyalkynylation and oxyarylation of propargylic amines. The reaction is perfectly regioselective based on the in-situ introduction of a hemiacetal tether derived from trifluoroacetaldehyde. Cis-selective carbo-oxygenation was achieved for terminal alkynes, whereas internal alkynes gave trans-carbo-oxygenation products. The obtained enol ethers could be easily transformed into 1,2-amino alcs. or α-amino ketones using hydrogenation or hydrolysis, resp.
Here is just a brief introduction to this compound(16400-32-1)Application In Synthesis of 1-Bromo-2-pentyne, more information about the compound(1-Bromo-2-pentyne) is in the article, you can click the link below.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics