Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, European Journal of Organic Chemistry called Synthesis of glycidol- and sugar-derived bicyclic β- and γ/δ-amino acids for peptidomimetic design, Author is Danieli, Elisa; Trabocchi, Andrea; Menchi, Gloria; Guarna, Antonio, which mentions a compound: 82954-65-2, SMILESS is NC[C@@H]1OC(C)(C)OC1, Molecular C6H13NO2, Related Products of 82954-65-2.
Constrained bicyclic β- and γ/δ-amino acids I (R = H or CH2OBn; Fmoc = fluorenylmethoxycarbonyl, Bn = benzyl) and II were developed using glycidol and sugar derivatives The synthetic strategies involved epoxide ring opening of a glycidol derivative, and subsequent coupling with sugar-derived amines, leading to di- or trisubstituted bicyclic scaffolds after cyclization with trifluoroacetic acid. Achievement of β- or γ/δ-amino acids was accomplished by changing the protecting group strategy of the starting materials. Compatibility of the scaffold with solid-phase peptide synthesis was assessed by preparing model peptidomimetics using acid- and base-labile resins, thus giving a new tool for peptidomimetic design.
There is still a lot of research devoted to this compound(SMILES：NC[C@@H]1OC(C)(C)OC1)Related Products of 82954-65-2, and with the development of science, more effects of this compound(82954-65-2) can be discovered.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics