Application In Synthesis of 1-Bromo-2-pentyne. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1-Bromo-2-pentyne, is researched, Molecular C5H7Br, CAS is 16400-32-1, about Distal Alkenyl C-H Functionalization via the Palladium/Norbornene Cooperative Catalysis. Author is Wu, Zhao; Fatuzzo, Nina; Dong, Guangbin.
A distal-selective alkenyl C-H arylation method was reported through a directed palladium/norbornene (Pd/NBE) cooperative catalysis. An usage of appropriate combination of the directing group and the NBE cocatalyst was the key feature of this method. A range of acyclic and cyclic cis-olefins were suitable substrates and the reaction was operated under air with excellent site-selectivity. Preliminary mechanistic studies were consistent with the proposed Pd/NBE-catalyzed C-H activation instead of the Heck pathway. Initial success on distal alkylation was achieved using MeI and Me bromoacetate as electrophiles.
There is still a lot of research devoted to this compound(SMILES：CCC#CCBr)Application In Synthesis of 1-Bromo-2-pentyne, and with the development of science, more effects of this compound(16400-32-1) can be discovered.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics