Yang, Guixiang; Liu, Ye; Wang, Liqun; Zhang, Yue; Ma, Xiaoming; Zhang, Wei published an article about the compound: 1-Bromo-2-pentyne( cas:16400-32-1,SMILESS:CCC#CCBr ).Application of 16400-32-1. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:16400-32-1) through the article.
Intermediates generated from three-component [3+2] cycloaddition of 2-bromo arylaldehydes such as 2-bromobenzaldehyde, 2-bromo-5-(trifluoromethyl)benzaldehyde, 2-bromonaphthalene-1-carbaldehyde, etc. and maleimides I (R = Me, Et, t-Bu, benzyl) with amino esters (Et 2-aminopropanoate hydrochloride) or amino acids (2-amino-2-methylpropanoic acid) underwent N-propargylation and reductive Heck cyclization to form pyrrolidinedione-fused hexahydropyrrolo[2,1-a]isoquinolines e.g., II.
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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics