In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Gold-Catalyzed Domino Cycloisomerization/Alkoxylation: An Entry to 3,4-Dihydro-1H-[1,4]oxazino[4,3-a]indole, published in 2021-12-17, which mentions a compound: 16400-32-1, mainly applied to dihydrooxazinoindole diastereoselective regioselective preparation; alc aldehydeyne domino cycloisomerization alkoxylation gold catalyst, Product Details of 16400-32-1.
A novel and mild synthetic route for the preparation of functionalized polycyclic indole skeletons via a gold-mediated cycloisomerization/alkoxylation of 1,6-aldehyde-yne had been developed. This atom-economical catalytic process that associates IPrAu(MeCN)BF4 and an alc. demonstrated remarkable selectivity in accessing functionalized 3,4-dihydro-1H-[1,4]oxazino[4,3-a]indole derivatives I [R1 = H, Et, Ph, etc.; R2 = H, Me, Br; R3 = H, Cl; R4 = Me, i-Pr, CH2CH=CH2, Bn, CH2CH(CH3)CH2CH3, CH2CH=CCH2CH2CH=C(Me)2] of high synthetic utility (21 examples, yields of ≤96%) and could be optimized under asym. conditions with an enantiomeric excess of ≤86%.
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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics