The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Bromo-5-methylpyrazine, is researched, Molecular C5H5BrN2, CAS is 98006-90-7, about An efficient and facile synthesis of 2-bromo-5-methylpyrazine, the main research direction is pyrazinecarboxylate preparation amidation; pyrazinecarboxamide preparation Hofmann degradation; aminomethylpyrazine preparation diazotization bromination; bromomethylpyrazine preparation; pyrazine bromo methyl preparation.Recommanded Product: 98006-90-7.
A facile and efficient synthesis of 2-bromo-5-methylpyrazine was described. The title compound was obtained by conversion of 5-methylpyrazine-2-carboxylate to the corresponding amide, which on Hofmann degradation gave the resp. amine. This amine on diazotization followed by in-situ bromination produced the targeted 2-bromo-5-methylpyrazine.
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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics