So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Doboszewski, Bogdan; Groaz, Elisabetta; Herdewijn, Piet researched the compound: (S)-(2,2-dimethyl-[1,3]-dioxolan-4-yl)-methylamine( cas:82954-65-2 ).SDS of cas: 82954-65-2.They published the article 《Synthesis of phosphonoglycine backbone units for the development of phosphono peptide nucleic acids》 about this compound( cas:82954-65-2 ) in European Journal of Organic Chemistry. Keywords: phosphonoglycine backbone enantioselective synthesis phosphono peptide nucleic acid; amino dihydroxy phosphonate nucleobase thymine; glycol phosphonylation alkylation peptide coupling galactose azidation Staudinger imination. We’ll tell you more about this compound (cas:82954-65-2).
A series of phosphono-modified backbone mimics based on achiral and chiral N-(dihydroxypropyl)glycine units were obtained by sequential addition of phosphonate and nucleobase moieties to suitably protected dihydroxypropylamines. Simple synthetic strategies enabled the preparation of various target derivatives that will be useful as building blocks for the preparation of new synthetic polymers containing a phosphonate internucleotide linkage in place of the standard phosphodiester bond.
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Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics