The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-Bromo-2-pentyne(SMILESS: CCC#CCBr,cas:16400-32-1) is researched.Quality Control of 1-Bromo-2-pentyne. The article 《Access to chiral cyano-containing five-membered rings through enantioconvergent rhodium-catalyzed cascade cyclization of a diastereoisomeric E/Z mixture of 1,6-enynes》 in relation to this compound, is published in Organic Chemistry Frontiers. Let’s take a look at the latest research on this compound (cas:16400-32-1).
In contrast to the intermol. rhodium-catalyzed asym. 1,4-addition of organometallic reagents to activated alkenes, the asym. arylative cyclization of diastereoisomeric E/Z mixture of 1,6-enynes afforded only one major enantiomer.
In addition to the literature in the link below, there is a lot of literature about this compound(1-Bromo-2-pentyne)Recommanded Product: 16400-32-1, illustrating the importance and wide applicability of this compound(16400-32-1).
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics