The important role of 50501-07-0

This literature about this compound(50501-07-0)Reference of Ethyl indoline-2-carboxylatehas given us a lot of inspiration, and I hope that the research on this compound(Ethyl indoline-2-carboxylate) can be further advanced. Maybe we can get more compounds in a similar way.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Isolation of a Bacillus Aryabhattai strain for the resolution of (R, S)-ethyl indoline-2-carboxylate to produce (S)-indoline-2-carboxylic acid, published in 2019, which mentions a compound: 50501-07-0, mainly applied to Bacillus Aryabhattai esterase perindopril, Reference of Ethyl indoline-2-carboxylate.

The strain screened from sludge can selectively hydrolyze (S)-Et indoline-2-carboxylate to produce (S)-indoline-2-carboxylic acid. It was identified as the Bacillus aryabhattai strain based on its morphol., metabolism, and 16S rDNA sequence anal. Glucose and yeast powder were used as the best carbon and nitrogen sources to cultured cells with an initial pH of seven. Subsequently, we optimized the key parameters for selective hydrolysis. Finally, when the substrate concentration had reached 3%, with a 35°C water bath, a pH of seven, and a speed of 600 rpm, the e.e.p value attained 96% with a 33% yield. Thus, we had developed a new method for producing (S)-indoline-2-carboxylic acid that used whole microbial cells as the biocatalyst.

This literature about this compound(50501-07-0)Reference of Ethyl indoline-2-carboxylatehas given us a lot of inspiration, and I hope that the research on this compound(Ethyl indoline-2-carboxylate) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics