Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 50501-07-0, is researched, SMILESS is O=C(C1NC2=C(C=CC=C2)C1)OCC, Molecular C11H13NO2Journal, Article, Bioorganic & Medicinal Chemistry Letters called Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones, Author is Gleave, D. Mark; Brickner, Steven J.; Manninen, Peter R.; Allwine, Debra A.; Lovasz, Kristine D.; Rohrer, Douglas C.; Tucker, John A.; Zurenko, Gary E.; Ford, Charles W., the main research direction is oxazolidinone fused conformationally restricted preparation antibacterial.SDS of cas: 50501-07-0.
A series of conformationally restricted, [6,5,5] and [6,6,5] tricyclic fused oxazolidinones were synthesized and tested for antibacterial activity. Several compounds, e.g. I, in the trans-[6,5,5] series demonstrated potent in vitro and in vivo activity. This work provides valuable information regarding the preferred conformational orientation of the oxazolidinones at the binding site.
This literature about this compound(50501-07-0)SDS of cas: 50501-07-0has given us a lot of inspiration, and I hope that the research on this compound(Ethyl indoline-2-carboxylate) can be further advanced. Maybe we can get more compounds in a similar way.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics