Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 97739-46-3, is researched, SMILESS is CC1(C2)OC(C3)(C)OC2(C)OC3(C)P1C4=CC=CC=C4, Molecular C16H21O3PJournal, Article, Research Support, U.S. Gov’t, Non-P.H.S., Journal of the American Chemical Society called Reversed-Polarity Synthesis of Diaryl Ketones via Palladium-Catalyzed Cross-Coupling of Acylsilanes, Author is Schmink, Jason R.; Krska, Shane W., the main research direction is diaryl ketone preparation reaction mechanism; acylsilane aryl bromide cross coupling palladium catalyst.HPLC of Formula: 97739-46-3.
Acylsilanes serve as acyl anion equivalent in a palladium-catalyzed cross-coupling reaction with aryl bromides to give unsym. diaryl ketones. Water plays a unique and crucial activating role in these reactions. High-throughput experimentation techniques provided successful reaction conditions initially involving phosphites as ligands. Ultimately, 1,3,5,7-tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantane was identified as giving a longer-lived catalyst with higher turnover numbers Its use, in conjunction with a palladacycle precatalyst, led to optimal reaction rates and yields. Scope and limitations of this novel method are presented along with initial mechanistic insight.
As far as I know, this compound(97739-46-3)HPLC of Formula: 97739-46-3 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics