Bognar, Balazs; Kalai, Tamas; Gulyas-Fekete, Gergely; Lazsanyi, Noemi; Hideg, Kalman published an article about the compound: Ethyl indoline-2-carboxylate( cas:50501-07-0,SMILESS:O=C(C1NC2=C(C=CC=C2)C1)OCC ).Safety of Ethyl indoline-2-carboxylate. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:50501-07-0) through the article.
Nitroxides connected to indoles, tetrazoles or 1,3,4-oxadiazoles were synthesized by conventional and microwave-assisted cyclization reactions. New approaches to pyrrole-, pyrazole-, and triazole-annulated nitroxides are described. The authors showed that a Diels-Alder reaction of a N-tert-butoxycarbonyl derivative of (4,4,6,6-tetramethyl-2,4,6,7-tetrahydro-5H-pyrrolo[3,4-c]pyridin-5-yl)oxidanyl gave polycyclic scaffolds condensed with a six-membered nitroxide. The synthesis of the target compounds was achieved using as starting materials 3-cyano-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy radical, 4-cyano-3,6-dihydro-2,2,6,6-tetramethyl-1(2H)-pyridinyloxy radical, 4-cyano-2,2,6,6-tetramethyl-1-piperidinyloxy radical (TEMPO derivative), 3-formyl-2,5-dihydro-2,2,5,5-tetramethyl-1H-pyrrol-1-yloxy radical and similar nitroxide radical derivatives The title compounds thus formed included triazole-nitroxide radical derivatives, benzotriazole-nitroxide radical derivatives, pyrrole-nitroxide radical derivatives, indole-nitroxide radical derivatives and related substances.
As far as I know, this compound(50501-07-0)Safety of Ethyl indoline-2-carboxylate can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics