The effect of the change of synthetic route on the product 16400-32-1

Compounds in my other articles are similar to this one(1-Bromo-2-pentyne)HPLC of Formula: 16400-32-1, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

HPLC of Formula: 16400-32-1. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1-Bromo-2-pentyne, is researched, Molecular C5H7Br, CAS is 16400-32-1, about Synthesis of Benzimidazole-Fused Medium-Sized N,S-Heterocycles via Palladium-Catalyzed Cyclizations.

The synthesis of unprecedented benzimidazole-fused thiazocines, e.g., I, thiazonines, and thiazecines having an exocyclic double bond is reported. The process proceeds through an 8-, 9-, or 10-exo-dig cyclocarbopalladation followed by reduction The scope and limitations were established and showed the importance of the precursor structure for the success of the reaction. A competition between the exo-dig and the endo-dig cyclization was observed for two substrates bearing an N-homopropargyl chain, the endo-cyclization leading to rarely encountered 10- and 11-membered N,S-heterocycles with a trans-endocyclic double bond. X-ray structures of three products were obtained by co-crystallization with fumaric acid and show the twisted structures of these mols.

Compounds in my other articles are similar to this one(1-Bromo-2-pentyne)HPLC of Formula: 16400-32-1, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics