In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Expedient Synthesis of α-Heteroaryl Piperidines Using a Pd-Catalyzed Suzuki Cross-Coupling-Reduction Sequence, published in 2014-01-17, which mentions a compound: 98006-90-7, mainly applied to piperidine heteroaryl preparation; heteroaryl bromide Suzuki boronate ester reduction palladium catalyst, Application of 98006-90-7.
A method for the modular synthesis of α-heteroaryl piperidines is reported. The two-step procedure consists of an initial Pd-catalyzed Suzuki cross-coupling of the heteroaryl bromide with a boronate ester derived from N-Boc-piperidone, followed by subsequent tetrahydropyridine reduction Using this method, α-heteroaryl piperidine products featuring a broad range of pharmaceutically relevant azine and diazine substitutions have been prepared
Compounds in my other articles are similar to this one(2-Bromo-5-methylpyrazine)Application of 98006-90-7, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics