The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-Bromo-2-pentyne, is researched, Molecular C5H7Br, CAS is 16400-32-1, about Palladium-Catalyzed Carbo-Oxygenation of Propargylic Amines using in Situ Tether Formation, the main research direction is propargylic amine hemiacetal haloalkyne palladium catalyst regioselective diastereoselective oxyalkynylation; alkynyloxazolidine preparation; alkynes; amino alcohols; palladium catalysis; stereoselective synthesis; tethers.Product Details of 16400-32-1.
This work reported a new method for the palladium-catalyzed oxyalkynylation and oxyarylation of propargylic amines. The reaction is perfectly regioselective based on the in-situ introduction of a hemiacetal tether derived from trifluoroacetaldehyde. Cis-selective carbo-oxygenation was achieved for terminal alkynes, whereas internal alkynes gave trans-carbo-oxygenation products. The obtained enol ethers could be easily transformed into 1,2-amino alcs. or α-amino ketones using hydrogenation or hydrolysis, resp.
After consulting a lot of data, we found that this compound(16400-32-1)Product Details of 16400-32-1 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics