Formula: C5H9BrOIn 2019 ,《Efficient Kinetic Resolution of Sulfur-Stereogenic Sulfoximines by Exploiting CpXRhIII-Catalyzed C-H Functionalization》 was published in Angewandte Chemie, International Edition. The article was written by Brauns, Marcus; Cramer, Nicolai. The article contains the following contents:
In the presence of a nonracemic cyclopentacyclooctadinaphthalene rhodium complex and N-phthalimido-L-phenylalanine, racemic aryl sulfoximines underwent kinetic resolution by C-H activation and cyclocondensation reactions with diazo compounds such as MeCOC(:N2)CO2Et in MeOH to yield nonracemic sulfoximines such as I and nonracemic benzothiazinones such as II. The method was used for the formal syntheses of two kinase inhibitors. After reading the article, we found that the author used 4-Bromotetrahydropyran(cas: 25637-16-5Formula: C5H9BrO)
4-Bromotetrahydropyran(cas: 25637-16-5) is often used as reactant for: nickel-catalyzed alkyl-alkyl Suzuki coupling reactions with boron reagents, preparation of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans; preparation of aliphatic hydrocarbons via nickel-catalyzed Suzuki cross-coupling with alkylboranes.Formula: C5H9BrO
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics