《Redox-Neutral Ni-Catalyzed sp3 C-H Alkylation of α-Olefins with Unactivated Alkyl Bromides》 was written by Buendia, Mikkel B.; Higginson, Bradley; Kegnaes, Soeren; Kramer, Soeren; Martin, Ruben. Safety of 4-BromotetrahydropyranThis research focused onunactivated alkene alkyl bromide hydrogen alkylation redox neutral nickel; regio chemoselective light induced redox neutral nickel alkene alkylation. The article conveys some information:
A light-induced redox-neutral Ni-catalyzed sp3 C-H alkylation of unactivated alkenes with alkyl bromides possessing β-hydrogens is described herein. The method is distinguished by its simplicity, wide scope, and exquisite regio- and chemoselectivity profile, thus offering an entry point to forge sp3-sp3 architectures. The results came from multiple reactions, including the reaction of 4-Bromotetrahydropyran(cas: 25637-16-5Safety of 4-Bromotetrahydropyran)
4-Bromotetrahydropyran(cas: 25637-16-5) is often used as reactant for: preparation of anthranilic acids as antibacterial agents with human serum albumin binding affinity; preparation of antiatherogenic antioxidant di-tert-butyldihydrobenzofuranols via Grignard reactions with di-tert-butyl(hydroxy)benzaldehyde derivatives; synthesis of gephyrotoxin via the Schmidt reaction.Safety of 4-Bromotetrahydropyran
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics