In 2022,Kancherla, Rajesh; Muralirajan, Krishnamoorthy; Rueping, Magnus published an article in Chemical Science. The title of the article was 《Excited-state palladium-catalysed reductive alkylation of imines: scope and mechanism》.Electric Literature of C5H9BrO The author mentioned the following in the article:
The development of excited-state palladium-catalyzed reductive alkylation of imines with alkyl bromides was described. The new methodol. showed broad functional group tolerance and was addnl. be applied in the direct three-component reaction of aldehydes, anilines and alkyl bromides to give the alkyl amines under mild reaction conditions. Time-resolved photoluminescence experiments allowed the determination of the excited-state reaction kinetics and indicate that the reaction was proceeded via the inner-sphere electron transfer mechanism. The experimental part of the paper was very detailed, including the reaction process of 4-Bromotetrahydropyran(cas: 25637-16-5Electric Literature of C5H9BrO)
4-Bromotetrahydropyran(cas: 25637-16-5) is often used as reactant for: nickel-catalyzed alkyl-alkyl Suzuki coupling reactions with boron reagents, preparation of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans; preparation of aliphatic hydrocarbons via nickel-catalyzed Suzuki cross-coupling with alkylboranes.Electric Literature of C5H9BrO
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics