《Visible-Light-Driven Reductive Carboarylation of Styrenes with CO2 and Aryl Halides》 was written by Wang, Hao; Gao, Yuzhen; Zhou, Chunlin; Li, Gang. Application In Synthesis of 4-Bromotetrahydropyran And the article was included in Journal of the American Chemical Society in 2020. The article conveys some information:
The first example of visible-light-driven reductive carboarylation of styrenes with CO2 and aryl halides in a regioselective manner has been achieved. A broad range of aryl iodides and bromides were compatible with this reaction. Moreover, pyridyl halides, alkyl halides, and even aryl chlorides were also viable with this method. These findings may stimulate the exploration of novel visible-light-driven Meerwein arylation-addition reactions with user-friendly aryl halides as the radical sources and the photocatalytic utilization of CO2. Thus, e.g., reaction of 1,1-diphenylethylene with PhI and CO2 under blue light in presence of [Ir(ppy)2(dtbbpy)]PF6 photocatalyst and hydrogen atom transfer catalyst DABCO with HCO2K as terminal reductant and K2CO3 as base in DMSO followed by methylation afforded I (82%, 78% isolated). In the experiment, the researchers used 4-Bromotetrahydropyran(cas: 25637-16-5Application In Synthesis of 4-Bromotetrahydropyran)
4-Bromotetrahydropyran(cas: 25637-16-5) is often used as reactant for: preparation of anthranilic acids as antibacterial agents with human serum albumin binding affinity; preparation of antiatherogenic antioxidant di-tert-butyldihydrobenzofuranols via Grignard reactions with di-tert-butyl(hydroxy)benzaldehyde derivatives; synthesis of gephyrotoxin via the Schmidt reaction.Application In Synthesis of 4-Bromotetrahydropyran
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics