In 2022,Zhou, Xiao; Guo, Lin; Zhang, Haoxiang; Xia, Raymond Yang; Yang, Chao; Xia, Wujiong published an article in Advanced Synthesis & Catalysis. The title of the article was 《Nickel-Catalyzed Reductive Acylation of Carboxylic Acids with Alkyl Halides and N-Hydroxyphthalimide Esters Enabled by Electrochemical Process》.Related Products of 25637-16-5 The author mentioned the following in the article:
A sustainable Ni-catalyzed reductive acylation reaction of carboxylic acids via an electrochem. pathway was presented, affording a ketones ArC(O)R [Ar = Ph, 4-MeC6H4, 4-PhC6H4, etc.; R = n-Bu, CH(Me)2, CH2Cy, etc.] as major products. The reaction proceeded at ambient temperature using unactivated alkyl halides and N-hydroxyphthalimide (NHP) esters as coupling partners, which exhibited several synthetic advantages, including mild conditions and convenience of amplification (58% yield for 6 mmol scale reaction). In the part of experimental materials, we found many familiar compounds, such as 4-Bromotetrahydropyran(cas: 25637-16-5Related Products of 25637-16-5)
4-Bromotetrahydropyran(cas: 25637-16-5) is often used as reactant for: preparation of anthranilic acids as antibacterial agents with human serum albumin binding affinity; preparation of antiatherogenic antioxidant di-tert-butyldihydrobenzofuranols via Grignard reactions with di-tert-butyl(hydroxy)benzaldehyde derivatives; synthesis of gephyrotoxin via the Schmidt reaction.Related Products of 25637-16-5
Referemce:
Tetrahydropyran – Wikipedia,
Tetrahydropyran – an overview | ScienceDirect Topics