Barton, Derek H. R.’s team published research in Journal of the Chemical Society [Section] C: Organic in | CAS: 27943-46-0

Journal of the Chemical Society [Section] C: Organic published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Product Details of C10H16O2.

Barton, Derek H. R. published the artcileSynthesis of the insect molting hormone, ecdysone, and related compounds, Product Details of C10H16O2, the publication is Journal of the Chemical Society [Section] C: Organic (1970), 1584-91, database is CAplus and MEDLINE.

A relatively short synthesis of the insect molting hormone, ecdysone, and of its C-22 isomer is described, starting from ergosterol. A key step is the direct transformation of the 3α,5α-cycloergosta-7,22-dien-6-one into the 14α- and 14β-ergosta-2,7,22-trien-6-ones. Selective cis-hydroxylation of the 2-enes, followed by enol acetylation and oxidation with perphthalic acid afforded the 5α-ecdysone nucleus. Ozonolysis of the C-22 double bond gave (20S)-2β,3β-diacetoxy-20-formyl-14α-hydroxy-5α-pregn-7-en-6-one, to which the ecdysone side chain was attached in a known manner.

Journal of the Chemical Society [Section] C: Organic published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, Product Details of C10H16O2.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics