Boutier, Audrey published the artcilePd-Catalyzed Asymmetric Synthesis of N-Allenyl Amides and Their Au-Catalyzed Cycloisomerizative Hydroalkylation: A New Route Toward Enantioenriched Pyrrolidones, HPLC of Formula: 27943-46-0, the publication is Chemistry – A European Journal (2012), 18(13), 3840-3844, S3840/1-S3840/66, database is CAplus and MEDLINE.
Au-catalyzed cycloisomerizative hydroalkylation of N-allenyl amides affords regioselectively 4-vinyl-γ-lactams. This transformation is stereospecific and takes place with total axis-to-center chirality transfer. The required enantioenriched N-allenyl amide is successfully obtained from Pd-catalyzed dynamic kinetic asym. allenylic amination. Overall this process is as follows: N-benzyl-2,2,2-trifluoroacetamide + (±)-n-pentyl-CH:C:CHCH2OAc → I (R = COCF3 e.r. 82:18) → I (R = COCH2COMe) → II (e.r. 81:19).
Chemistry – A European Journal published new progress about 27943-46-0. 27943-46-0 belongs to tetrahydropyran, auxiliary class Tetrahydropyran,Alkynyl,Ether, name is 2-((2-Methylbut-3-yn-2-yl)oxy)tetrahydro-2H-pyran, and the molecular formula is C10H16O2, HPLC of Formula: 27943-46-0.
Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics