Khan, Muhammad Kamran’s team published research in Journal of Agricultural and Food Chemistry in 58 | CAS: 69097-99-0

Khan, Muhammad Kamran published the artcileChemical Synthesis of Citrus Flavanone Glucuronides, Application In Synthesis of 69097-99-0, the publication is Journal of Agricultural and Food Chemistry (2010), 58(14), 8437-8443, database is CAplus and MEDLINE.

Flavanone glucuronides are the major phenolic metabolites detected in human plasma after consumption of citrus fruits. As such, they might display significant cardioprotective effects. In this work, glucuronides of naringenin (4′- and 7-O-β-D-glucuronides) and hesperetin (3′- and 7-O-β-D-glucuronides), the major flavanone aglycons in grapefruit and orange, resp., have been chem. synthesized. On the one hand, the most reactive hydroxyl group, C7-OH, was protected by selective benzoylation to allow subsequent glucuronidation of C4′-OH (naringenin) or C3′-OH (hesperetin) (B-ring). On the other hand, the selective debenzoylation at C₇-OH of the per-benzoylated flavanone aglycons allowed glucuronidation at the same position (A-ring). After careful deprotection, the target compounds were purified and characterized by NMR and mass spectrometry.

Journal of Agricultural and Food Chemistry published new progress about 69097-99-0. 69097-99-0 belongs to tetrahydropyran, auxiliary class Other Aliphatic Heterocyclic,Benzene,Phenol,Ether,Inhibitor, name is 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one, and the molecular formula is C16H14O6, Application In Synthesis of 69097-99-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydropyran,
Tetrahydropyran – an overview | ScienceDirect Topics